| 172 | 0 | 23 |
| 下载次数 | 被引频次 | 阅读次数 |
目的 探索长时间静坐对抑郁焦虑症状的影响，揭示静坐时长与抑郁焦虑症状风险的剂量反应关系。方法 基于2022年全国普通人群网络调查，使用简易量表评估抑郁症状和焦虑症状，采用Logistic回归模型分析长时间静坐对抑郁或焦虑症状的影响，在探索重要特征交互作用基础上，进行分层分析，使用限制性立方样条法刻画静坐时长与抑郁或焦虑症状风险的剂量反应关系。结果 共纳入平均年龄36.3岁的40 123名成人。多因素Logistic回归模型结果显示，相比于平均每天静坐时长<4 h，静坐时长≥8 h能增加20%的抑郁症状风险(OR=1.20,95%CI:1.12-1.30)和16%的焦虑症状风险(OR=1.16,95%CI:1.07-1.25)，平均每天静坐时长与抑郁症状或焦虑症状均呈U型剂量反应关系(P_总<0.05,P非线性<0.05)。分层分析结合剂量反应关系显示，相比于男性，女性人群长时间静坐与抑郁症状的风险关联更强;更高收入群体、非体力劳动工作者以及无慢病史人群中发现了更强的长时间静坐与抑郁或焦虑症状风险的关联。结论 长时间静坐能带来不良的心理健康影响，为预防精神心理问题，应在合理范围内减少静坐时长，增加身体活动。
Abstract：Objective To explore the impact of prolonged sitting on the depressive and anxiety symptoms and reveal the dose-response relationship between the duration of sitting and the risk of depressive and anxiety symptoms. Methods Based on the 2022 national online survey of the general population,the simple scale was used to assess depressive and anxiety symptoms. The Logistic regression model was adopted to analyze the impact of prolonged sitting on depressive or anxiety symptoms. On the basis of exploring the interaction of important characteristics,a stratified analysis was conducted.The dose-response relationship between sitting time and the risk of depressive or anxiety symptoms was depicted using the restrictive cubic spline method. Results A total of 40,123 adults with an average age of 36. 3 years were included. The results of the multivariate Logistic regression model showed that,compared with a daily sedentary duration of less than 4 hours,Sitting for ≥8 hours can increase the risk of depressive symptoms by 20%( OR = 1. 20,95% CI: 1. 12-1. 30) and the risk of anxiety symptoms by 16%( OR = 1. 16,95% CI: 1. 07-1. 25). The daily sedentary duration showed a U-shaped dose-response relationship with both depressive symptoms and anxiety symptoms( Ptotal< 0. 05,Pnon-linear< 0. 05). Stratified analysis combined with dose-response relationship showed that compared with men,the risk of prolonged sitting in the female population was more strongly associated with depressive symptoms. A stronger association between prolonged sitting and the risk of depressive or anxiety symptoms was found among higher-income groups,non-manual labor workers,and people without a history of chronic diseases. Conclusion Prolonged sitting can have adverse effects on mental health. To prevent mental and psychological problems,the duration of sitting should be reduced within a reasonable range and physical activities should be increased.
[1]Global,regional,and national burden of 12 mental disorders in 204 countries and territories,1990-2019:a systematic analysis for the Global Burden of Disease Study 2019[J]. Lancet Psychiatry,2022,9(2):137-150.
[2]Deng Y,Sun S,Wu S,et al. Burden and trends of mental disorders in China from 1990 to 2019:findings from the Global Burden of Disease Study 2019[J]. Soc Psychiatry Psychiatr Epidemiol,2024,59(9):1563-1576.
[3]刘熠华，云青萍，张蓝超，等．久坐行为与体育锻炼行为对职业人群焦虑倾向的联合作用[J]．北京大学学报(医学版)，2022,54(3):490-497.
[4]Cao Z,Xu C,Zhang P,et al. Associations of sedentary time and physical activity with adverse health conditions:outcome-wide analyses using isotemporal substitution model[J]. EClinical Medicine,2022,48:101424.
[5]Chen X,Gao H,Shu B,et al. Effects of changes in physical and sedentary behaviors on mental health and life satisfaction during the COVID-19 pandemic:evidence from China[J]. PLo S One,2022,17(6):e0269237.
[6]Cano-Vindel A,Mu noz-Navarro R,Medrano LA,et al. A computerized version of the Patient Health Questionnaire-4 as an ultrabrief screening tool to detect emotional disorders in primary care[J]. J Affect Disord,2018,234:247-255.
[7]Casanova F,O'loughlin J,Karageorgiou V,et al. Effects of physical activity and sedentary time on depression,anxiety and wellbeing:a bidirectional Mendelian randomisation study[J]. BMC Med,2023,21(1):501.
[8]Li Q,Zhao Z,Yang C,et al. Sedentary behavior and risk of depression in older adults:a systematic meta-analysis[J]. Iran J Public Health,2024,53(2):293-304.
[9]Allen MS,Walter EE,Swann C. Sedentary behaviour and risk of anxiety:a systematic review and meta-analysis[J]. J Affect Disord,2019,242:5-13.
[10]Rees-Punia E,Patel A V,Nocera JR,et al. Self-reported physical activity,sitting time,and mental and physical health among older cancer survivors compared with adults without a history of cancer[J]. Cancer,2021,127(1):115-123.
[11]Biddle SJ H,Henson J,Davies MJ,et al. Device-assessed total and prolonged sitting time:associations with anxiety,depression,and health-related quality of life in adults[J]. J Affect Disord,2021,287:107-114.
[12]Konopka MJ,K¨ohler S,Stehouwer CDA,et al. Accelerometer-derived sedentary time and physical activity and the incidence of depressive symptoms-The Maastricht Study[J]. Psychol Med,2020,52(13):1-8.
[13]Hallgren M,Nguyen TT,Owen N,et al. Associations of interruptions to leisure-time sedentary behaviour with symptoms of depression and anxiety[J]. Transl Psychiatry,2020,10(1):128.
[14]Vancampfort D,Stubbs B,Mugisha J,et al. Leisure-time sedentary behavior and suicide attempt among 126,392 adolescents in 43countries[J]. J Affect Disord,2019,250:346-353.
[15]Guo Y,Cheng C,Zeng Y,et al. Mental health disorders and associated risk factors in quarantined adults during the COVID-19outbreak in China:cross-sectional study[J]. J Med Internet Res,2020,22(8):e20328.
基本信息:
DOI：10.13936/j.cnki.cjdd1992.2026.01.009
中图分类号:R749
引用信息:
[1]吴水琳,宋金龙,黄越彤,等.中国成人静坐时长与抑郁焦虑症状的关联分析[J].中国药物依赖性杂志,2026,35(01):38-46.DOI:10.13936/j.cnki.cjdd1992.2026.01.009.
基金信息:
国家自然科学基金(82171514,82471550)
2025-12-15
2025-12-15
2025-12-15